DNA is bound to tiny particles of gold or tungsten which are subsequently shot into plant tissue or single plant cells under high pressure.  The eight Neolithic founder crops (emmer wheat, einkorn wheat, barley, peas, lentils, bitter vetch, chick peas and flax) had all appeared by about 7,000 BC. 2013 was the second year in which developing countries grew a majority (54%) of the total GM harvest. GM cotton began growing in India in 2002, reaching 110,000 km2 in 2013.  It was developed creating a chimeric gene that joined an antibiotic resistant gene to the T1 plasmid from Agrobacterium. ", "Genetic Engineering for Maize Improvement in China", "FDA approves Protalix Gaucher treatment", "Julian Ma: I'm growing antibodies in tobacco plants to help prevent HIV", "GM microbe breakthrough paves way for large-scale seaweed farming for biofuels", "Singapore Biodiesel Company Develops GM Jatropha- Crop Biotech Update", "Genetically modified crops' results raise concern", "Suppression of CINNAMOYL-CoA REDUCTASE increases the level of monolignol ferulates incorporated into maize lignins", "Scientists engineer plants to eat toxic pollution", "New grasses neutralize toxic pollution from bombs, explosives, and munitions", "Genomic Insights into Oil Biodegradation in Marine Systems", "Rapid breeding of parthenocarpic tomato plants using CRISPR/Cas9", "GM Crops List | GM Approval Database- ISAAA.org", "UPDATE 3-U.S. farmers get approval to plant GMO alfalfa", "Infographics: Global Status of Commercialized Biotech/GM Crops: 2014 - ISAAA Brief 49-2014 | ISAAA.org", "Executive Summary: Global Status of Commercialized Biotech/GM Crops: 2014 - ISAAA Brief 49-2014 | ISAAA.org", "Genetically Engineered Crops in the United States (summary)", "Insect resistance to transgenic Bt crops: lessons from the laboratory and field", 10.1002/(SICI)1096-9063(199711)51:3<328::AID-PS650>3.0.CO;2-B, "Monsanto - Pink Bollworm Resistance to GM Cotton in India", "The Real Deal: Explaining Monsanto's Refuge-in-the-Bag Concept", "Understanding successful resistance management: the European corn borer and Bt corn in the United States", "Resistance evolution to the first generation of genetically modified Diabrotica-active Bt-maize events by western corn rootworm: management and monitoring considerations", "Conservation Tillage, Herbicide Use, and Genetically Engineered Crops in the United States: The Case of Soybeans", "Adoption of Genetically Engineered Crops in the U.S.", "Roundup Ready soybean trait patent nears expiration in 2014", "USDA ERS - Adoption of Genetically Engineered Crops in the U.S.", "USA :Cultivation of GM Plants in 2009, Maize, soybean, cotton: 88 percent genetically modified", "Adoption of Genetically Engineered Crops in the U.S. – Recent Trends", "Genetic engineering: the future of foods? Some micro-organisms have a version of EPSPS that is resistant to glyphosate inhibition. , Yields increased 9% for herbicide tolerance and 25% for insect resistant varieties. Plant genomes can be engineered by physical methods or by use of Agrobacterium for the delivery of sequences hosted in T-DNA binary vectors. , Golden rice, developed by the International Rice Research Institute (IRRI), provides greater amounts of vitamin A targeted at reducing vitamin A deficiency. Next Up: French Fry Fans", "J.R. 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This represents a 19.4% reduction in insecticide use. Another method is to use a bacterium or virus. Regulation varies in a given country depending on the intended use of each product. The meta-analysis considered all published English-language examinations of the agronomic and economic impacts between 1995 and March 2014 for three major GM crops: soybean, maize, and cotton. Agricultural Biotechnology: Meeting the Needs of the Poor. They attempted to correct for publication bias, by considering sources beyond academic journals.  Camelina sativa has been modified to produce plants that accumulate high levels of oils similar to fish oils.  They serve as model organisms for other plant species. , In the late 1990s, a genetically modified potato that was resistant to the Colorado potato beetle was withdrawn because major buyers rejected it, fearing consumer opposition. , A genetically modified cassava under development offers lower cyanogen glucosides and enhanced protein and other nutrients (called BioCassava).  Some studies have claimed that genetically modified crops can cause harm; a 2016 review that reanalyzed the data from six of these studies found that their statistical methodologies were flawed and did not demonstrate harm, and said that conclusions about GM crop safety should be drawn from "the totality of the evidence... instead of far-fetched evidence from single studies".. On rare occasions, the process of DNA transfer can happen without deliberate human intervention. There are other ways to change the genomes of crops, some of which are long established, such as mutational breeding, and others of which are new, such as genome editing, but in this Q&A we are focusing on GM as it is currently usually defined for regulatory purposes in Europe. "An Illusory Consensus behind GMO Health Assessment". , Companies that produce Bt seed are introducing strains with multiple Bt proteins. See Genetically modified food controversies article for information. "Published GMO studies find no evidence of harm when corrected for multiple comparisons".  The United States enacted a law that requires labeling regulations to be issued by July 2018. The number of sites per release and the number of gene constructs (ways that the gene of interest is packaged together with other elements) – have rapidly increased since 2005. The request includes plans for avoiding herbicide drift to other crops. Here, we show that a number of articles some of which have strongly and negatively influenced the public opinion on GM crops and even provoked political actions, such as GMO embargo, share common flaws in the statistical evaluation of the data.